Home Antibody All anti-PSMB7 antibodies
Anti-PSMB7 TRUEMAB Antibody Clone 4D12
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for PSMB7 (NM_002799)
|Human recombinant protein fragment corresponding to amino acids 58-277 of human PSMB7(NP_002790) produced in E.coli.|
|Human , Monkey , Mouse
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens proteasome (prosome, macropain) subunit, beta type, 7 (PSMB7)|
Entrez Gene 5695 Human
Entrez Gene 19177 Mouse
Entrez Gene 694567 Monkey
|The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit). [provided by RefSeq]. |
|ProteaseDruggable Genome Proteasome|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PSMB7 (RC201799, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PSMB7.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-PSMB7 monoclonal antibody.