Anti-RUVBL2 Antibody, Clone 1A6

Also for RUVBL2 (NM_006666)

OriGene Data

Immunogen	Human recombinant protein fragmengt corresponding to amino acids 113-370 of human RUVBL2(NP_006657) produced in E.coli.
Clone Name	Clone 1A6	Isotype	IgG1
Species Reactivity	Human , Dog , Rat , Monkey , Mouse	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC, IF, FC	Suggested Dilutions	WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens RuvB-like 2 (E. coli) (RUVBL2)
Alternative Name	CGI-46; ECP51; INO80J; REPTIN; RVB2; TIH2; TIP48; TIP49B
Database Link	NP_006657
Function	This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq].
Related Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RUVBL2 (RC200933, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RUVBL2.

WB Image

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-RUVBL2 monoclonal antibody.

IHC Image

Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-RUVBL2 mouse monoclonal antibody. (TA504281)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-RUVBL2 mouse monoclonal antibody. (TA504281)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-RUVBL2 mouse monoclonal antibody. (TA504281)

IHC Image

Immunohistochemical staining of paraffin-embedded Human tonsil using anti-RUVBL2 mouse monoclonal antibody. (TA504281)

IF Image

Anti-RUVBL2 mouse monoclonal antibody (TA504281) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RUVBL2(RC200933).

FC Image

HEK293T cells transfected with either RC200933 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-RUVBL2 antibody(TA504281), and then analyzed by flow cytometry.

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Anti-RUVBL2 TrueMAB Antibody Clone 1A6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data