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Anti-C1S TRUEMAB Antibody Clone OTI2D11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA504246 C1S mouse monoclonal antibody, clone OTI2D11 (formerly 2D11) 100ul $325 In Stock
LC400655 C1S HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504246 Carrier-free (BSA/glycerol-free) C1S mouse monoclonal antibody, clone OTI2D11 (formerly 2D11) 100ug $450 3-4 weeks
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WB(2)
IHC(5)
FC(2)

OriGene Data

ImmunogenFull length human recombinant protein of human C1S(NP_001725) produced in HEK293T cell.
Clone NameClone OTI2D11 IsotypeIgG2a
Species ReactivityHuman Concentration1.2 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:2000, IHC 1:150, FLOW 1:100,
Predicted MW Explanation 74.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens complement component 1, s subcomponent (C1S), transcript variant 2
Alternative NameFLJ44757
Database LinkNP_001725
Entrez Gene 716 Human
FunctionThis gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq].
Related PathwayProteaseDruggable Genome Complement and coagulation cascadesSystemic lupus erythematosus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C1S (RC218963, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C1S.
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Western blot analysis of extracts (10ug) from 6 different cell lines by using anti-C1S monoclonal antibody.(1:200)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504246)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504246)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504246)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504246)
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504246)
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Flow cytometric Analysis of Hela cells, using anti-C1S antibody(TA504246),(Red), compared to a nonspecific negative control antibody,(Blue).
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Flow cytometric Analysis of Jurkat cells, using anti-C1S antibody(TA504246),(Red), compared to a nonspecific negative control antibody,(Blue).
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