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Home Antibody All anti-CYP17A1 antibodies

Anti-CYP17A1 TRUEMAB Antibody clone 5G10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503415
  • CYP17A1 mouse monoclonal antibody,clone 5G10
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400030) , 20ug Explanation
100ul 325 In Stock
CF503415
  • Carrier-free (BSA/glycerol-free) CYP17A1 mouse monoclonal antibody,clone 5G10
100ug $450 3-4 weeks
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WB(1)
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Also for CYP17A1 (NM_000102)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human CYP17A1(NP_000093) produced in HEK293T cell.
Clone Nameclone 5G10 IsotypeIgG1
Species ReactivityHuman Concentration0.65 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:2000,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1)
Alternative NameCPT7; CYP17; P450C17; S17AH
Database LinkNP_000093
Entrez Gene 1586 Human
FunctionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq].
Related PathwayP450Druggable Genome C21-Steroid hormone metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP17A1 (RC209042, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP17A1.

 

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