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Home Antibody All anti-DOK2 antibodies

Anti-DOK2 TRUEMAB Antibody Clone OTI2D10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA503381 DOK2 mouse monoclonal antibody, clone OTI2D10 (formerly 2D10) 100ul $379 In Stock
LC418321 DOK2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF503381 Carrier-free (BSA/glycerol-free) DOK2 mouse monoclonal antibody, clone OTI2D10 (formerly 2D10) 100ug $450 3-4 weeks
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WB(2)

OriGene Data

ImmunogenFull length human recombinant protein of human DOK2(NP_003965) produced in HEK293T cell.
Clone NameClone OTI2D10 IsotypeIgG1
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration0.43 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:200~500,
Predicted MW Explanation 45.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens docking protein 2, 56kDa (DOK2)
Alternative Namep56DOK; p56dok-2
Database LinkNP_003965
Entrez Gene 9046 Human
Entrez Gene 13449 Mouse
Entrez Gene 290361 Rat
Entrez Gene 706317 Monkey
Entrez Gene 486133 Dog
FunctionThe protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DOK2 (RC207621, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DOK2.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-DOK2 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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