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Anti-PNPO TRUEMAB Antibody Clone OTI2F8
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for PNPO (NM_018129)
|Full length human recombinant protein of human PNPO(NP_060599) produced in HEK293T cell.|
|WB, IF, FC
||WB 1:500, IF 1:100, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens pyridoxamine 5'-phosphate oxidase (PNPO)|
Entrez Gene 55163 Human
|The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.|
| Vitamin B6 metabolismMetabolic pathways|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PNPO (RC200133, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PNPO.
Anti-PNPO mouse monoclonal antibody (TA503178) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PNPO(RC200133).
HEK293T cells transfected with either RC200133 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PNPO antibody(TA503178), and then analyzed by flow cytometry.