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Home Antibody All anti-MVK antibodies

Anti-MVK TRUEMAB Antibody Clone OTI 1D7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA502934 MVK mouse monoclonal antibody, clone OTI 1D7 (formerly 1D7) 100ul $379 In Stock
LC424723 MVK HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502934 Carrier-free (BSA/glycerol-free) MVK mouse monoclonal antibody, clone OTI 1D7 (formerly 1D7) 100ug $450 3-4 weeks
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WB(2)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human MVK (NP_000422) produced in HEK293T cell.
Clone NameClone OTI 1D7 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:2000, IF 1:100,
Predicted MW Explanation 42.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens mevalonate kinase (MVK), transcript variant 1
Alternative NameLRBP; MK; MVLK; POROK3
Database LinkNP_000422
Entrez Gene 4598 Human
FunctionThis gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome Terpenoid backbone biosynthesisMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MVK (RC201971, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MVK.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MVK monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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Anti-MVK mouse monoclonal antibody (TA502934) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MVK(RC201971).
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