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Home Antibody All anti-RPS6KB1 antibodies

Anti-RPS6KB1 TRUEMAB Antibody Clone OTI4G4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502930 RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI4G4 (formerly 4G4) 100ul $325 In Stock
LC401097 RPS6KB1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502930 Carrier-free (BSA/glycerol-free) RPS6KB1 mouse monoclonal antibody, clone OTI4G4 (formerly 4G4) 100ug $450 3-4 weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IF(1)
FC(1)
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Also for RPS6KB1 (NM_003161)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human RPS6KB1 (NP_003152) produced in HEK293T cell.
Clone NameClone OTI4G4 IsotypeIgG1
Species ReactivityHuman Concentration0.91 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 59 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1), transcript variant 1
Alternative Namep70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A
Database LinkNP_003152
Entrez Gene 6198 Human
FunctionThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome ErbB signaling pathwaymTOR signaling pathwayTGF-beta signaling pathwayFc gamma R-mediated phagocytosisInsulin signaling pathwayAcute myeloid leukemiaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RPS6KB1 (RC217324, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RPS6KB1.
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Anti-RPS6KB1 mouse monoclonal antibody (TA502930) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RPS6KB1(RC217324 ).
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HEK293T cells transfected with either RC217324 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-RPS6KB1 antibody(TA502930), and then analyzed by flow cytometry.
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