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Anti-RASSF1 TRUEMAB Antibody clone 8A11
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for RASSF1 (NM_007182)
|Full length human recombinant protein of human RASSF1 (NP_009113) produced in E.coli.|
||WB 1:500, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A|
|123F2; NORE2A; RASSF1A; RDA32; REH3P21|
Entrez Gene 11186 Human
|This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.|
|Druggable Genome Pathways in cancerBladder cancerNon-small cell lung cancer|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RASSF1 (RC213525, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RASSF1.
Anti-RASSF1 mouse monoclonal antibody (TA502512) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RASSF1(RC213525).