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Home Antibody All anti-RASSF1 antibodies

Anti-RASSF1 TRUEMAB Antibody clone 8A11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502512
  • RASSF1 mouse monoclonal antibody, clone 8A11
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402099) , 20ug
100ul 325 In Stock
CF502512
  • Carrier-free (BSA/glycerol-free) RASSF1 mouse monoclonal antibody, clone 8A11
100ug $450 3-4 weeks
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WB(1)
IF(1)
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Also for RASSF1 (NM_007182)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human RASSF1 (NP_009113) produced in E.coli.
Clone Nameclone 8A11 IsotypeIgG1
Species ReactivityHuman Concentration0.88 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:500, IF 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A
Alternative Name123F2; NORE2A; RASSF1A; RDA32; REH3P21
Database LinkNP_009113
FunctionThis gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Related Pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RASSF1 (RC213525, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RASSF1.
IF Image
Anti-RASSF1 mouse monoclonal antibody (TA502512) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RASSF1(RC213525).

 

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