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Home Antibody All anti-RASSF1 antibodies

Anti-RASSF1 TRUEMAB Antibody Clone OTI3C2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA502480 RASSF1 mouse monoclonal antibody, clone OTI3C2 (formerly 3C2) 100ul 325
In Stock
LC402099 RASSF1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502480 Carrier-free (BSA/glycerol-free) RASSF1 mouse monoclonal antibody, clone OTI3C2 (formerly 3C2) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human RASSF1 (NP_009113) produced in E.coli.
Clone NameClone OTI3C2 IsotypeIgG1
Species ReactivityHuman Concentration0.48 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:500, IF 1:100,
Predicted MW Explanation 38.6 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A
Alternative Name123F2; NORE2A; RASSF1A; RDA32; REH3P21
Database LinkNP_009113
Entrez Gene 11186 Human
FunctionThis gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Related PathwayDruggable Genome Pathways in cancerBladder cancerNon-small cell lung cancer

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* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RASSF1 (RC213525, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RASSF1.
Anti-RASSF1 mouse monoclonal antibody (TA502480) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RASSF1(RC213525).


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