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Anti-CTH TRUEMAB Antibody Clone OTI1E12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502442 CTH (Cystathionase) mouse monoclonal antibody, clone OTI1E12 (formerly 1E12) 100ul $379 In Stock
LC419669 CTH HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502442 Carrier-free (BSA/glycerol-free) CTH mouse monoclonal antibody, clone OTI1E12 (formerly 1E12) 100ug $450 3-4 weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(2)
IHC(9)

OriGene Data

ImmunogenFull length human recombinant protein of human CTH (NP_001893) produced in HEK293T cell.
Clone NameClone OTI1E12 IsotypeIgG2b
Species ReactivityHuman , Dog , Monkey Concentration0.32 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:500~2000, IHC 1:150,
Predicted MW Explanation 44.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cystathionine gamma-lyase (CTH), transcript variant 1
Alternative NameMGC9471
Database LinkNP_001893
Entrez Gene 1491 Human
Entrez Gene 479991 Dog
FunctionThis gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010].
Related Pathway Glycine, serine and threonine metabolismCysteine and methionine metabolismSelenoamino acid metabolismNitrogen metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTH (RC202195, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTH.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CTH monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CTH mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502442)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-CTH mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502442)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-CTH mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502442)
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-CTH mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502442)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CTH mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502442)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-CTH mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502442)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-CTH mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502442)
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Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-CTH mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502442)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CTH mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502442)
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