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Home Antibody All anti-CTNNB1 antibodies

Anti-CTNNB1 CONJUGATED Antibody clone 12H7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502409S
  • CTNNB1 mouse monoclonal antibody, clone 12H7
30ul 120 In Stock
CF502409
  • Carrier-free (BSA/glycerol-free) CTNNB1 mouse monoclonal antibody, clone 12H7
30ulug $450 3 Days
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Also for CTNNB1 (NM_001904)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human CTNNB1 (NP_001895) produced in HEK293T cell.
Clone Nameclone 12H7 IsotypeIgG1
Species ReactivityHuman , Rat , Monkey Concentration1mg/ml
Guaranteed Application * Suggested Dilutions
Buffer
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1
Alternative Namearmadillo; CTNNB; MRD19
Database LinkNP_001895
FunctionThe protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
Related Pathway
Adherens junction
Adipogenesis
Focal Adhesion
Melanogenesis
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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