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Anti-GPHN TRUEMAB Antibody Clone OTI7B6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA502284 GPHN (Gephyrin) mouse monoclonal antibody, clone OTI7B6 (formerly 7B6) 100ul 325
In Stock
LC402806 GPHN HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502284 Carrier-free (BSA/glycerol-free) GPHN mouse monoclonal antibody, clone OTI7B6 (formerly 7B6) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human GPHN (NP_065857) produced in HEK293T cell.
Clone NameClone OTI7B6 IsotypeIgG2a
Species ReactivityHuman Concentration0.76 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:2000, FLOW 1:100
Predicted MW Explanation 83.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens gephyrin (GPHN), transcript variant 1
Database LinkNP_065857
Entrez Gene 10243 Human
FunctionThis gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GPHN (RC205986, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GPHN.
HEK293T cells transfected with either RC205986 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-GPHN antibody(TA502284), and then analyzed by flow cytometry.


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