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Home Antibody All anti-GPHN antibodies

Anti-GPHN TRUEMAB Antibody clone 3B6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502217
  • GPHN (Gephyrin) mouse monoclonal antibody, clone 3B6
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402806) , 20ug Explanation
100ul 379 In Stock
CF502217
  • Carrier-free (BSA/glycerol-free) GPHN mouse monoclonal antibody, clone 3B6
100ug $450 3-4 weeks
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(2)
IHC(4)
IF(1)
FC(2)
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Also for GPHN (NM_020806)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human GPHN (NP_065857) produced in HEK293T cell.
Clone Nameclone 3B6 IsotypeIgG2a
Species ReactivityHuman, Monkey Concentration0.61 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Predicted MW Explanation 83.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens gephyrin (GPHN), transcript variant 1
Alternative NameGEPH; GPH; GPHRYN; HKPX1; MOCODC
Database LinkNP_065857
Entrez Gene 10243 Human
Entrez Gene 709677 Monkey
FunctionThis gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GPHN (RC205986, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GPHN.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-GPHN monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-GPHN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502217)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-GPHN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502217)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-GPHN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502217)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-GPHN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502217)
IF Image
Anti-GPHN mouse monoclonal antibody (TA502217) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GPHN(RC205986).
FC Image
HEK293T cells transfected with either RC205986 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-GPHN antibody(TA502217), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-GPHN antibody(TA502217),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).

 

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