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Anti-MYD88 TRUEMAB Antibody Clone OTI1A10
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for MYD88 (NM_002468)
|Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.|
|WB, IHC, FC
||WB 1:2000, IHC 1:150, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens myeloid differentiation primary response 88 (MYD88), transcript variant 2|
Entrez Gene 4615 Human
|This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq].|
|Druggable Genome ApoptosisToll-like receptor signaling pathway|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MYD88 (RC202253, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MYD88.
Western blot analysis of extracts (10ug) from 2 different cell lines by using anti-MYD88 monoclonal antibody.(1:200)
Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-MYD88 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502116)
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MYD88 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502116)
HEK293T cells transfected with either RC202253 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-MYD88 antibody(TA502116), and then analyzed by flow cytometry.
Flow cytometric Analysis of Hela cells, using anti-MYD88 antibody(TA502116),(Red), compared to a nonspecific negative control antibody,(Blue).
Flow cytometric Analysis of Jurkat cells, using anti-MYD88 antibody(TA502116),(Red), compared to a nonspecific negative control antibody,(Blue).