Anti-RNH1 Antibody, clone 1B7

Also for RNH1 (NM_002939)

Gene Name	Homo sapiens ribonuclease/angiogenin inhibitor 1 (RNH1), transcript variant 1
Synonyms:	RAI; RNH
Immunogen	Full length human recombinant protein of human RNH1 (NP_002930) produced in HEK293T cell.
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Name	clone 1B7	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *	WB, IHC, IF, FC	Suggested Dilutions	WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Background	Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM].
Related Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RNH1 (RC208360, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RNH1.

WB Image

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-RNH1 monoclonal antibody.

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-RNH1 mouse monoclonal antibody. (TA501981)

IHC Image

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-RNH1 mouse monoclonal antibody. (TA501981)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-RNH1 mouse monoclonal antibody. (TA501981)

IHC Image

Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-RNH1 mouse monoclonal antibody. (TA501981)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-RNH1 mouse monoclonal antibody. (TA501981)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-RNH1 mouse monoclonal antibody. (TA501981)

IHC Image

Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-RNH1 mouse monoclonal antibody. (TA501981)

IHC Image

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-RNH1 mouse monoclonal antibody. (TA501981)

IF Image

Anti-RNH1 mouse monoclonal antibody (TA501981) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RNH1(RC208360).

FC Image

HEK293T cells transfected with either RC208360 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-RNH1 antibody(TA501981), and then analyzed by flow cytometry.

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Anti-RNH1 TrueMAB Antibody clone 1B7

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