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Home Antibody All anti-DCX antibodies

Anti-DCX TRUEMAB Antibody clone 4A3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA501778
  • DCX mouse monoclonal antibody, clone 4A3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403598) , 20ug Explanation
100ul 379 In Stock
CF501778
  • Carrier-free (BSA/glycerol-free) DCX mouse monoclonal antibody, clone 4A3
100ug $450 3-4 weeks
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
IF(1)
FC(1)
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Also for DCX (NM_178152)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human DCX (NP_835365) produced in HEK293T cell.
Clone Nameclone 4A3 IsotypeIgG1
Species ReactivityHuman Concentration0.73 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 40.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens doublecortin (DCX), transcript variant 2
Alternative NameDBCN; DC; LISX; SCLH; XLIS
Database LinkNP_835365
Entrez Gene 1641 Human
FunctionThis gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DCX (RC221891, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DCX.
IF Image
Anti-DCX mouse monoclonal antibody (TA501778) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DCX(RC221891).
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-DCX antibody(TA501778),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).

 

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