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Home Antibody All anti-L1CAM antibodies

Anti-L1CAM TRUEMAB Antibody Clone OTI2A5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA501438 L1CAM mouse monoclonal antibody, clone OTI2A5 (formerly 2A5) 100ul $325 In Stock
LC400150 L1CAM HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501438 Carrier-free (BSA/glycerol-free) L1CAM mouse monoclonal antibody, clone OTI2A5 (formerly 2A5) 100ug $450 3-4 weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(2)
FC(2)
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Also for L1CAM (NM_000425)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human L1CAM (NP_000416) produced in HEK293T cell.
Clone NameClone OTI2A5 IsotypeIgG1
Species ReactivityHuman, Monkey Concentration0.76 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:500~2000, FLOW 1:100
Predicted MW Explanation 137.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1
Alternative NameCAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1
Database LinkNP_000416
Entrez Gene 3897 Human
Entrez Gene 697504 Monkey
FunctionThe protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq].
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Axon guidanceCell adhesion molecules (CAMs)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY L1CAM (RC211601, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-L1CAM.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-L1CAM monoclonal antibody.
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HEK293T cells transfected with either RC211601 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-L1CAM antibody(TA501438), and then analyzed by flow cytometry.
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Flow cytometric Analysis of Hela cells, using anti-L1CAM antibody(TA501438),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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