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Home Antibody All anti-FADD antibodies

Anti-FADD TRUEMAB Antibody clone 1C11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA501434
  • anti-FADD mouse monoclonal antibody, clone 1C11
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401265) , 20ug Explanation
100ul 379 In Stock
CF501434
  • Carrier-free (BSA/glycerol-free) FADD mouse monoclonal antibody, clone 1C11
100ug $450 3-4 weeks
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WB(1)
FC(1)
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Also for FADD (NM_003824)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human FADD (NP_003815) produced in HEK293T cell.
Clone Nameclone 1C11 IsotypeIgG1
Species ReactivityHuman Concentration0.63 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:2000, FLOW 1:100
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens Fas (TNFRSF6)-associated via death domain (FADD)
Alternative NameGIG3; MORT1
Database LinkNP_003815
Entrez Gene 8772 Human
FunctionThe protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq].
Related Pathway
Apoptosis
Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FADD (RC201805, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FADD.
FC Image
HEK293T cells transfected with either RC201805 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-FADD antibody(TA501434), and then analyzed by flow cytometry.

 

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