Home Antibody All anti-COX6A1 antibodies
Anti-COX6A1 TRUEMAB Antibody clone 4G2
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for COX6A1 (NM_004373)
|Full length human recombinant protein of human COX6A1 (NP_004364) produced in HEK293T cell.|
|WB, IF, FC
||WB 1:500, IF 1:100, FLOW 1:100
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens cytochrome c oxidase subunit VIa polypeptide 1 (COX6A1)|
|CMTRID; COX6A; COX6AL|
Entrez Gene 1337 Human
|Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. [provided by RefSeq].|
|Transmembrane Oxidative phosphorylationMetabolic pathwaysCardiac muscle contractionAlzheimer's diseaseParkinson's diseaseHuntington's diseaseMore Pathways >> |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY COX6A1 (RC210485, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-COX6A1.
Anti-COX6A1 mouse monoclonal antibody (TA501431) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY COX6A1(RC210485).
HEK293T cells transfected with either RC210485 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-COX6A1 antibody(TA501431), and then analyzed by flow cytometry.