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Home Antibody All anti-RIC8A antibodies

Anti-RIC8A TRUEMAB Antibody Clone 3G3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA501055
  • anti-RIC8A (RIC8) mouse monoclonal antibody, Clone 3G3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402886) , 20ug
100ul $379 In Stock
CF501055
  • Carrier-free (BSA/glycerol-free) RIC8A mouse monoclonal antibody, clone 3G3
100ug $450 3-4 Days
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WB(1)
IHC(1)
IF(2)
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Also for RIC8A (NM_021932)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human RIC8A (NP_068751) produced in HEK293T cell.
Clone NameClone 3G3 IsotypeIgG1
Species ReactivityHuman Concentration0.83mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:1000, IHC 1:50, IF 1:100,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.05% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens RIC8 guanine nucleotide exchange factor A (RIC8A), transcript variant 1
Alternative NameRIC8
Database LinkNP_068751
FunctionGuanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RIC8A (RC211359, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RIC8A.
IHC Image
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-RIC8A mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501055, Dilution 1:50)
IF Image
Anti-RIC8A mouse monoclonal antibody (TA501055) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RIC8A(RC211359).
IF Image
Immunofluorescent staining of HepG2 cells using anti-RIC8A mouse monoclonal antibody (TA501055).

 

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