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Home Antibody All anti-MCL1 antibodies

Anti-MCL1 TRUEMAB Antibody Clone OTI10D10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500990 anti-MCL1 mouse monoclonal antibody, clone OTI10D10 (formerly 10D10) 100ul $325 In Stock
LC411855 MCL1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500990 Carrier-free (BSA/glycerol-free) MCL1 mouse monoclonal antibody, clone OTI10D10 (formerly 10D10) 100ug $450 3-4 weeks
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WB(2)
IF(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human MCL1 (NP_068779) produced in HEK293T cell.
Clone NameClone OTI10D10 IsotypeIgG2a
Species ReactivityHuman Concentration0.95 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, Flow 1:100
Predicted MW Explanation 37.3 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens myeloid cell leukemia 1 (MCL1), transcript variant 1
Alternative Namebcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1-ES; mcl1/EAT; MCL1L; MCL1S; TM
Database LinkNP_068779
Entrez Gene 4170 Human
FunctionThe protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MCL1 (RC200521, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MCL1.
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Western blot analysis of extracts (10ug) from 8 different cell lines by using anti-MCL1 monoclonal antibody at 1:200 dilution.
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Anti-MCL1 mouse monoclonal antibody (TA500990) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MCL1(RC200521).
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HEK293T cells transfected with either pCMV6-ENTRY MCL1(RC200521)(Red) or empty vector control plasmid(Blue) were immunostained with anti-MCL1 mouse monoclonal(TA500990), and then analyzed by flow cytometry.
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