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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-MCL1 antibodies

Anti-MCL1 TrueMAB Antibody Clone 2E11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA500986
  • Purified anti-MCL1 mouse monoclonal antibody, clone 2E11
  • FREE positive control: HEK293T cell transient overexpression lysate (LC411855) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF500986
  • Carrier-free (BSA/glycerol-free) MCL1 mouse monoclonal antibody, clone 2E11
100ug $450 3-4 weeks Add to Shopping Cart
WB(1)
IHC(13)
IF(2)
FC(3)
Gene NameHomo sapiens myeloid cell leukemia sequence 1 (BCL2-related) (MCL1), nuclear gene encoding mitochondrial protein, transcript variant 1
Synonyms:bcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1-ES; mcl1/EAT; MCL1L; MCL1S; TM
ImmunogenFull length human recombinant protein of human MCL1 (NP_068779) produced in HEK293T cell.
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 2E11 IsotypeIgG2a
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:50, IF 1:100, Flow 1:100
BackgroundThe protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
Related Pathway
Apoptosis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MCL1 (RC200521, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MCL1.
IHC Image
Immunohistochemical staining of paraffin-embedded breast tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded colon tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded lung tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of pancreas tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded thyroid tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded bladder tissue using anti-MCL1 mouse monoclonal antibody. (TA500986, Dilution 1:50)
IF Image
Anti-MCL1 mouse monoclonal antibody (TA500986) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MCL1(RC200521).
IF Image
Immunofluorescent staining of HepG2 cells using anti-MCL1 mouse monoclonal antibody (TA500986).
FC Image
HEK293T cells transfected with either pCMV6-ENTRY MCL1(RC200521)(Red) or empty vector control plasmid(Blue) were immunostained with anti-MCL1 mouse monoclonal(TA500986), and then analyzed by flow cytometry.
FC Image
Flow cytometric analysis of Hela cells, using anti-MCL1 antibody(TA500986),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).
FC Image
Flow cytometric analysis of Jurkat cells, using anti-MCL1 antibody(TA500986),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).

 

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