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Home Antibody All anti-IDH3A antibodies

Anti-IDH3A TRUEMAB Antibody clone 2E9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500912
  • anti-IDH3A mouse monoclonal antibody, clone 2E9
100ul 325 In Stock
CF500912
  • Carrier-free (BSA/glycerol-free) IDH3A mouse monoclonal antibody, clone 2E9
100ug $450 3-4 weeks
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IF(1)
FC(1)
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Also for IDH3A (NM_005530)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human IDH3A (NP_005521) produced in HEK293T cell.
Clone Nameclone 2E9 IsotypeIgG1
Species ReactivityHuman Concentration0.60 mg/ml
Guaranteed Application *IF, FC Suggested DilutionsIF 1:100, Flow 1:100
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens isocitrate dehydrogenase 3 (NAD+) alpha (IDH3A)
Alternative NameH-IDH alpha; NAD(H)-specific isocitrate dehydrogenase alpha subunit; NAD+-specific ICDH; isocitrate dehydrogenase (NAD+) alpha chain; isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; isocitric dehydrogenase; isocitrate dehydrogenase 3 (NAD+) a
Database LinkNP_005521
FunctionIsocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Related Pathway

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IF Image
Anti-IDH3A mouse monoclonal antibody (TA500912) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IDH3A(RC200313).
FC Image
HEK293T cells transfected with either pCMV6-ENTRY IDH3A(RC200313)(Red) or empty vector control plasmid(Blue) were immunostained with anti-IDH3A mouse monoclonal(TA500912), and then analyzed by flow cytometry.

 

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