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Home Antibody All anti-RNF144B antibodies

Anti-RNF144B TRUEMAB Antibody Clone OTI10A12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500706 RNF144B (IBRDC2) mouse monoclonal antibody, clone OTI10A12 (formerly 10A12) 100ul $325 In Stock
LC405351 RNF144B HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500706 Carrier-free (BSA/glycerol-free) RNF144B mouse monoclonal antibody, clone OTI10A12 (formerly 10A12) 100ug $450 3-4 weeks
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WB(1)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-256 of human RNF144B (NP_877434) produced in E. coli.
Clone NameClone OTI10A12 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:100,
Predicted MW Explanation 33.7 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens ring finger protein 144B (RNF144B)
Alternative NamebA528A10.3; IBRDC2; p53RFP; PIR2
Database LinkNP_877434
Entrez Gene 255488 Human
FunctionE3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism.
Related PathwayTransmembrane

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* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RNF144B (RC209302, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RNF144B.
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