Anti-SSX2 Antibody, clone 4A11

Also for SSX2 (NM_003147)

OriGene Data

Immunogen	Protein expressed in 293T cell transfected with human SSX2 expression vector
Clone Name	clone 4A11	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB 1:2000, IHC 1:50, IF 1:100,
Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens synovial sarcoma, X breakpoint 2 (SSX2), transcript variant 1
Alternative Name	CT5.2a; HD21; HOM-MEL-40; SSX
Database Link	NP_003138
Function	The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Related Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SSX2 (RC201214, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SSX2.

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-SSX2 mouse monoclonal antibody. (TA500618, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded colon tissue using anti-SSX2mouse monoclonal antibody. (TA500618, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-SSX2mouse monoclonal antibody. (TA500618, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-SSX2mouse monoclonal antibody. (TA500618, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-SSX2mouse monoclonal antibody. (TA500618, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded endometrium tissue using anti-SSX2mouse monoclonal antibody. (TA500618, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded prostate tissue using anti-SSX2mouse monoclonal antibody. (TA500618, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of bladder tissue using anti-SSX2mouse monoclonal antibody. (TA500618, Dilution 1:50)

IF Image

Anti-SSX2 mouse monoclonal antibody (TA500618) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SSX2(RC201214).

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FITC
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DyLight® 594
DyLight® 633

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OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-SSX2 TrueMAB Antibody clone 4A11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data