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Home Antibody All anti-KDM4C antibodies

Anti-KDM4C TRUEMAB Antibody clone 8A1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500588
  • anti-KDM4C mouse monoclonal antibody, clone 8A1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402405) , 20ug Explanation
100ul 325 In Stock
CF500588
  • Carrier-free (BSA/glycerol-free) KDM4C mouse monoclonal antibody, clone 8A1
100ug $450 3-4 weeks
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WB(1)
IHC(4)
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Also for KDM4C (NM_015061)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull-length protein expressed in 293T cell transfected with human KDM4C expression vector
Clone Nameclone 8A1 IsotypeIgG1
Species ReactivityHuman Concentration0.6 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:500, IHC 1:50,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1
Alternative NamebA146B14.1; GASC1; JHDM3C; JMJD2C; TDRD14C
Database LinkNP_055876
Entrez Gene 23081 Human
FunctionThis gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KDM4C (RC211182, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KDM4C .
IHC Image
Immunohistochemical staining of paraffin-embedded colon tissue using anti-KDM4C mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500588, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-KDM4C mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500588, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded endometrium tissue using anti-KDM4C mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500588, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-KDM4C mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500588, Dilution 1:50)

 

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