Anti-NTRK3 Antibody, clone 4E10

Also for NTRK3 (NM_001007156)

OriGene Data

Immunogen	Protein expressed in 293T cell transfected with human NTRK3 expression vector
Clone Name	clone 4E10	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB 1:1000 IHC 1:50 IF 1:100
Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 3
Alternative Name	gp145(trkC); TRKC
Database Link	NP_001007157
Function	This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Related Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NTRK3 (RC203781, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NTRK3.

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-NTRK3 mouse monoclonal antibody. (TA500538, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-NTRK3mouse monoclonal antibody. (TA500538, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of kidney tissue using anti-NTRK3mouse monoclonal antibody. (TA500538, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of lung tissue using anti-NTRK3mouse monoclonal antibody. (TA500538, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-NTRK3mouse monoclonal antibody. (TA500538, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of pancreas tissue using anti-NTRK3mouse monoclonal antibody. (TA500538, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-NTRK3mouse monoclonal antibody. (TA500538, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of prostate tissue using anti-NTRK3mouse monoclonal antibody. (TA500538, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of bladder tissue using anti-NTRK3mouse monoclonal antibody. (TA500538, Dilution 1:50)

IF Image

Anti-NTRK3 mouse monoclonal antibody (TA500538) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NTRK3(RC203781).

IF Image

Immunofluorescent staining of HT29 cells using anti-NTRK3 mouse monoclonal antibody (TA500538).

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Anti-NTRK3 TrueMAB Antibody clone 4E10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data