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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-SLC7A8 antibodies

Anti-SLC7A8 TrueMAB Antibody clone 7D6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA500515
  • Purified anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone 7D6
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402177) , 20ug
 100ul $325 In Stock Add to Shopping Cart
CF500515
  • Carrier-free (BSA/glycerol-free) SLC7A8 mouse monoclonal antibody, clone 7D6
100ug $450 3-4 weeks Add to Shopping Cart
WB(1)
IHC(11)
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Also for SLC7A8 (NM_012244)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody
Gene NameHomo sapiens solute carrier family 7 (amino acid transporter light chain, L system), member 8 (SLC7A8), transcript variant 1
Synonyms:LAT2; LPI-PC1
ImmunogenProtein expressed in 293T cell transfected with human SLC7A8 expression vector
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Nameclone 7D6 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:500, IHC 1:50,
BackgroundSodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine orD,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.
Related Pathway
Hemostasis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SLC7A8 (RC208586, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SLC7A8.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-SLC7A8 mouse monoclonal antibody. (TA500515, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded colon tissue using anti-SLC7A8mouse monoclonal antibody. (TA500515, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-SLC7A8mouse monoclonal antibody. (TA500515, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-SLC7A8mouse monoclonal antibody. (TA500515, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-SLC7A8mouse monoclonal antibody. (TA500515, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-SLC7A8mouse monoclonal antibody. (TA500515, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-SLC7A8mouse monoclonal antibody. (TA500515, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded endometrium tissue using anti-SLC7A8mouse monoclonal antibody. (TA500515, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of endometrium tissue using anti-SLC7A8mouse monoclonal antibody. (TA500515, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-SLC7A8mouse monoclonal antibody. (TA500515, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of bladder tissue using anti-SLC7A8mouse monoclonal antibody. (TA500515, Dilution 1:50)

 

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