Anti-STK39 Antibody, clone 2E10

Also for STK39 (NM_013233)

OriGene Data

Immunogen	Protein expressed in 293T cell transfected with human STK39 expression vector
Clone Name	clone 2E10	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB 1:2000 IHC 1:50
Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens serine threonine kinase 39 (STK39)
Alternative Name	DCHT; PASK; SPAK
Database Link	NP_037365
Function	This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.
Related Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STK39 (RC223981, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-STK39.

WB Image

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-STK39 monoclonal antibody.

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-STK39 mouse monoclonal antibody. (TA500497, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded colon tissue using anti-STK39mouse monoclonal antibody. (TA500497, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-STK39mouse monoclonal antibody. (TA500497, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-STK39mouse monoclonal antibody. (TA500497, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-STK39mouse monoclonal antibody. (TA500497, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-STK39mouse monoclonal antibody. (TA500497, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded endometrium tissue using anti-STK39mouse monoclonal antibody. (TA500497, Dilution 1:50)

Conjugation Services
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OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-STK39 TrueMAB Antibody clone 2E10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data