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Home Antibody All anti-CTNNB1 antibodies

Anti-CTNNB1 TRUEMAB Antibody Clone OTI3G4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500240 anti-Beta-catenin mouse monoclonal antibody, clone OTI3G4 (formerly 3G4) 100ul $325 In Stock
LC419662 CTNNB1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500240 Carrier-free (BSA/glycerol-free) Beta-catenin mouse monoclonal antibody, clone OTI3G4 (formerly 3G4) 100ug $450 8-10 Days
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WB(1)
IF(1)
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Also for CTNNB1 (NM_001904)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant protein expressed in E.coli corresponding to amino acids 531-781 of human beta-catenin
Clone NameClone OTI3G4 IsotypeIgG1
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:1000
Predicted MW Explanation 85.3 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1
Alternative Namearmadillo; CTNNB; MRD19
Database LinkNP_001895
Entrez Gene 1499 Human
FunctionBeta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete
Related PathwayES Cell Differentiation/IPSTranscription FactorsDruggable Genome Wnt signaling pathwayFocal adhesionAdherens junctionTight junctionLeukocyte transendothelial migrationMelanogenesisMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTNNB1 (RC208947, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTNNB1.
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Anti-CTNNB1 mouse monoclonal antibody (TA500240) immunofluorescent staining (Green) of COS7 cells transiently transfected by pCMV6-ENTRY CTNNB1(RC208947). (The nuclei were counter-stained in red.)
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