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Home Antibody All anti-Notch1 antibodies

Anti-Notch1 TRUEMAB Antibody clone 3E12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (1) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500078
  • anti-Notch1 mouse monoclonal antibody,clone 3E12
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402602) , 20ug
100ul
30ul
379 In Stock
CF500078
  • Carrier-free (BSA/glycerol-free) Notch1 mouse monoclonal antibody,clone 3E12
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(14)
IF(1)
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Also for Notch1 (NM_017617)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant protein expressed in E.coli corresponding to amino acids 2300-2556 of human NOTCH1
Clone Nameclone 3E12 IsotypeIgG2b
Species ReactivityHuman Concentration0.20mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000; IHC 1;50; RPPA 1:75; IF (1:100)
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Puridied form mouse ascites fluids

Reference Data

Target NameHomo sapiens notch 1 (NOTCH1)
Alternative NamehN1; TAN1
Database LinkNP_060087
FunctionNotch1 is a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development
Related Pathway
Delta-Notch Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Notch1(RC211365) (RC211365, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Notch1.
IHC Image
Immunohistochemical staining of paraffin-embedded breast using anti-Notch1 (TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast using anti-Notch1 (TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded colon using anti-Notch1(TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon using anti-Notch1 (TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded kidney using anti-Notch1 (TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of kidney using anti-Notch1 (TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded lung using anti-Notch1 (TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of lung using anti-Notch1 (TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary using anti-Notch1(TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded pancreas using anti-Notch1(TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of pancreas using anti-Notch1(TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded thyroid using anti-Notch1 (TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid using anti-Notch1 (TA500078) mouse monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded endometrium using anti-Notch1 (TA500078) mouse monoclonal antibody.
IF Image
Anti-Notch1 mouse monoclonal antibody (TA500078) immunofluorescent staining of HeLa cells transiently transfected by pCMV6-ENTRY Notch1(RC211365)

 

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