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Anti-PDX1 TRUEMAB Antibody clone 5D5
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for PDX1 (NM_000209)
|Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.|
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens pancreatic and duodenal homeobox 1 (PDX1)|
|GSF; IDX-1; IPF1; IUF1; MODY4; PDX-1; STF-1|
|Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDX1 (RC222354, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDX1.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-PDX1 monoclonal antibody.