FGF2 Mouse Monoclonal Antibody [Clone ID: OTI2H11]

CAT#: TA500013

bFGF (FGF2) mouse monoclonal antibody, clone OTI2H11 (formerly 2H11)

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free

Conjugation: Unconjugated Biotin HRP


  View other "OTI2H11" antibodies (4)

USD 447.00

In Stock*

Size
    • 100 ul

Product Images

Frequently bought together (3)
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Specifications

Product Data
Clone Name OTI2H11
Applications WB
Recommended Dilution WB 1:5000~10000
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 10-155 of human bFGF (NP_001997) produced in E.coli.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 30.6 kDa
Gene Name fibroblast growth factor 2
Background BFGF is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Synonyms BFGF; FGF-2; FGFB; HBGF-2
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

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