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Anti-POU5F1 Antibody Poly6319
Also for POU5F1 (NM_002701)
||Lot dependent; please refer to CoA along with shipment
|This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 50% glycerol.|
|The antibody was purified by antigen-affinity chromatography.
|Homo sapiens POU class 5 homeobox 1 (POU5F1), transcript variant 1|
|Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4|
Entrez Gene 5460 Human
|Oct4 (Octamer binding transcription factor 4) is an important marker of the undifferentiated state and a central regulator of pluripotency in ES cells. When embryonic stem cells are triggered to differentiate, Oct-4 is downregulated thus providing a model for the early events linked to somatic differentiation in the developing embryo. Oct4 is nucleus protein, with a predicted molecular weight 39 kD. The poly6318 antibody recognizes human Oct4 and has been shown to be useful for immunofluorescent staining.|
Wnt Signaling Pathway
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Immunofluorescent microscope analysis of NTERA-2 cells using anti-Oct4 polyclonal antibody (poly6319) (red). α-tubulin (clone 10D8) has been labeled with green, and nuclei were stained with DAPI (blue).