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Anti-F13A1 Antibody EP3372
Also for F13A1 (NM_000129)
||Lot dependent; please refer to CoA along with shipment
||IHC: 1:100 - 1:500
|The antibody is diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <1% sodium azide.|
|Factor XIIIa is a blood proenzyme that has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present in monocytes, macrophages, and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (90% (+)), dermatofibrosarcoma protuberans (25%(+)), and desmoplastic malignant melanoma (0%(+)). Anti-factor XIIIa positivity is also seen in capillary hemangioblastoma (100%(+)), hemangioendothelioma (100%(+)), hemangiopericytoma (100%(+)), xanthogranuloma (100%(+)), xanthoma (100%(+)), hepatocellular carcinoma (93%(+)), glomus tumor (80%(+)), and meningioma (80 % (+)).
|Homo sapiens coagulation factor XIII, A1 polypeptide (F13A1)|
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Immunohistochemistry staining of Paraffin Dermatofibroma tissue by Factor XIIIa antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic)