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Anti-Kcnb1 Antibody S89-34
Also for Kcnb1 (NM_013186)
|Synthetic peptide amino acids 837-853 (cytoplamsic C-terminus) of rat KV2.1 (HMLPGGGAHGSTRDQSI), |
|Human, Mouse, Rat
||WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
|PBS pH7.4, 50% glycerol|
|Protein G Purified
|Detects ~105-125kDa (varies with cell background due to phosphorylation). No cross reactivity to rat Kv2.2.
|Rattus norvegicus potassium voltage gated channel, Shab-related subfamily, member 1 (Kcnb1)|
|DRK1PC; Kcr1-1; Kv2.1; Shab|
|Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alphasubunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1- KV4 subfamilies generate functional K+ channels in a homotetrameric configuration. The KV2 subfamily consists of KV2.1 and KV2.2, and both have very similar properties. Members of the KV2 subfamily are widely expressed in neuronal tissues. They have also been reported in neurons in the dorsal root ganglia .|
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Western blot analysis of Kv2.1 on rat brain membrane tissues using a 1:1000 dilution of the antibody
IHC analysis of Kv2.1 using the antibody