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Home Antibody All anti-Grin1 antibodies

Anti-Grin1 Antibody S308-48


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SKU Description Amount Price Availability*  
TA326536 Mouse Monoclonal Anti-GluN1-NR1 Antibody 100µg $325 3-7 Days
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OriGene Data

ImmunogenFusion protein amino acids 42-361 (extracellular N-terminus) of rat NR1
Clone NameS308-48 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application *WB Suggested DilutionsWB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
BufferPBS pH7.4, 50% glycerol
Purification Protein G Purified
Note Detects ~105kDa.

Reference Data

Target NameRattus norvegicus glutamate ionotropic receptor NMDA type subunit 1 (Grin1), transcript variant 2
Alternative NameGluN1; NMDAR1; NR1
Database LinkNP_058706
Entrez Gene 2902 Human
Entrez Gene 14810 Mouse
Entrez Gene 24408 Rat
FunctionThe NMDA receptor (NMDAR), a glutamate receptor, is the predominant molecular device for controllingsynaptic plasticity and memory function . The NMDA receptor forms a heterotetramer between two NR1 andtwo NR2 subunits (the subunits are also called glutamatebinding NMDA receptor subunits or GluN for short); twoobligatory NR1 subunits and two regionally localized NR2 subunits. A related gene family of NR3 A and B subunitshave an inhibitory effect on receptor activity. Multiple receptor isoforms with distinct brain distributions andfunctional properties arise by selective splicing of the NR1 transcripts and differential expression of the NR2subunits.
Related Pathway

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WB Image
Western blot analysis of GluN1-NR1 in rat brain membrane tissues, using a 1:1000 dilution of the antibody


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