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Anti-Gria2 Antibody S21-32
Also for Gria2 (NM_017261)
|Fusion protein amino acids 834-883 (cytoplasmic C-terminus) of rat GluR2 |
|Human, Mouse, Rat
||WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
|PBS pH7.4, 50% glycerol|
|Protein G Purified
|Rattus norvegicus glutamate receptor, ionotropic, AMPA 2 (Gria2), transcript variant 1|
|GluA2; gluR-B; GluR-K2; GluR2|
|The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers . GluR2 is possibly the most important AMPA receptor subunit, responsible for AMPA receptor rectifying properties, control of ion flow and in particular, the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2 form, containing a critical arginine residue in the transmembrane region 2 domain, thereby rendering native AMPA receptors impermeable to calcium .|
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Western blot analysis of GluR2 on rat brain membrane tissues using a 1:1000 dilution of the antibody
IHC analysis of GluR2 using the antibody,tested on mouse cerebellum. Staining of neurons and fibers.
IHC analysis of GluR2 using the antibody,tested on mouse cerebellum. Staining of hippocampus: only some neurons appear to be positive to the antibody.