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Anti-FYN PHOSPHO Antibody
|The antiserum was produced against A synthesized peptide derived from human Fyn around the phosphorylation site of Tyrosine 530|
|Human, Mouse, Rat
||WB: 1:500-1:2000; IHC: 1:50-1:200
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens FYN oncogene related to SRC, FGR, YES (FYN), transcript variant 1|
|p59-FYN; SLK; SYN|
|FANCD2 Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress.|
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Western blot analysis of Fyn phosphorylation expression in H2O2 treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.