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Anti-CXCR2 PHOSPHO Antibody
Also for CXCR2 (NM_001168298)
|The antiserum was produced against A synthesized peptide derived from human IL-8R beta/CDw128 beta around the phosphorylation site of Serine 347|
||WB: 1:500-1:2000; IHC: 1:50-1:200; IF/ICC: 1:100-1:500
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens chemokine (C-X-C motif) receptor 2 (CXCR2), transcript variant 2|
|CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB|
|IL-8R B Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.|
Cytokine-cytokine receptor interaction
Signaling by GPCR
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Western blot analysis of IL-8R beta/CDw128 beta phosphorylation expression in PMA treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.