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Home Antibody All anti-BCL2A1 antibodies

Anti-BCL2A1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323788
  • Anti-BCL2A1 rabbit polyclonal antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC426506) , 20ug Explanation
100ul 325 2-3 Weeks
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WB(1)
IHC(1)
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Also for BCL2A1 (NM_001114735)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 1-175 amino acids of human BCL2-related protein A1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.7mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:2000-5000, WB: 1:200-1000,IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens BCL2-related protein A1 (BCL2A1), transcript variant 2
Alternative NameACC-1; ACC-2; BCL2L5; BFL1; GRS; HBPA1
Database LinkNP_001108207
Entrez Gene 597 Human
Entrez Gene 170929 Rat
FunctionThis gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 20 kDa . Positive control: Mouse testis tissue and hela cell lysate. Recommended dilution: 1/200-1000. (Gel: 12%SDS-PAGE Lane1: Mouse testis tissue lysate Lane2: Hela cell lysate Lysates: 40 ug per lane Primary antibody: 1/117 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using BCL2A1 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification:x200)

 

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