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Home Antibody All anti-BCL2A1 antibodies

Anti-BCL2A1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323788
  • Anti-BCL2A1 rabbit polyclonal antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC426506) , 20ug Explanation
100ul 325 2-3 Weeks
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WB(1)
IHC(1)
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Also for BCL2A1 (NM_001114735)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 1-175 amino acids of human BCL2-related protein A1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.7mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:2000-5000, WB: 1:200-1000,IHC: 1:25-100
Predicted MW Explanation 20kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens BCL2-related protein A1 (BCL2A1), transcript variant 2
Alternative NameACC-1; ACC-2; BCL2L5; BFL1; GRS; HBPA1
Database LinkNP_001108207
Entrez Gene 597 Human
Entrez Gene 170929 Rat
FunctionThis gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Related PathwayDruggable Genome Metabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 20 kDa . Positive control: Mouse testis tissue and hela cell lysate. Recommended dilution: 1/200-1000. (Gel: 12%SDS-PAGE Lane1: Mouse testis tissue lysate Lane2: Hela cell lysate Lysates: 40 ug per lane Primary antibody: 1/117 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using BCL2A1 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification:x200)

 

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