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Anti-HFE Antibody

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SKU Description Amount Price Availability*  
TA323661
  • Anti-HFE Rabbit Polyclonal Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424725) , 20ug
100ul 325 In Stock
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WB(1)
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Also for HFE (NM_000410)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 80-306 amino acids of human hemochromatosis
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration1.61mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-2000
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens hemochromatosis (HFE), transcript variant 1
Alternative NameHFE1; HH; HLA-H; MVCD7; TFQTL2
Database LinkNP_000401
FunctionThe protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Related Pathway

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WB Image
Predicted band size: 40 kDa . Positive control: Hela, A375 and Caco-2 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: Hela cell lysate Lane2: A375 cell lysate Lane3: Caco-2 cell lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

 

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