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Home Antibody All anti-NEFL antibodies

Anti-NEFL Antibody

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SKU Description Amount Price Availability*  
TA322530 Anti-NEFL Rabbit Polyclonal Antibody 100ul $325 In Stock
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IHC(2)

OriGene Data

ImmunogenFull length fusion protein
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.6mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:2000-5000, IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens neurofilament, light polypeptide (NEFL)
Alternative NameCMT1F; CMT2E; NF-L; NF68; NFL; PPP1R110
Database LinkNP_006149
Entrez Gene 4747 Human
Entrez Gene 18039 Mouse
Entrez Gene 83613 Rat
FunctionNeurofilaments are type IV intermediate filament heteropolymers composed of light; medium; and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E); disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Related PathwayES Cell Differentiation/IPSDruggable Genome Amyotrophic lateral sclerosis (ALS)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


IHC Image
Predicted cell location: Cell membrane. Positive control: Human Colon and esophagus cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human Colon and esophagus cancer tissue using NEFL antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification: x200)
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IHC Image
Predicted cell location: Cell membrane. Positive control: Human Colon and esophagus cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human Colon and esophagus cancer tissue using NEFL antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification: x200)
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