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Home Antibody All anti-ENPP6 antibodies

Anti-ENPP6 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA322012
  • Anti-ENPP6 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(1)
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Also for ENPP6 (NM_153343)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 119-419 amino acids of human ectonucleotide pyrophosphatase/phosphodiesterase 6
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.6mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-2000, IHC: 1:10-50
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6)
Alternative NameNPP6
Database LinkNP_699174
FunctionCholine-specific glycerophosphodiester phosphodiesterase. Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid; showing it has a lysophospholipase C activity. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C; p-nitrophenyl phosphorylcholine in vitro; while it does not hydrolyze the classical nucleotide phosphodiesterase substrate; p-nitrophenyl thymidine 5'-monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine; phosphatidylinositol; phosphatidylserine; phosphatidylglycerol and phosphatidic acid.
Related Pathway

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IHC Image
Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human cervical cancer tissue. Recommended dilution: 1/10-50 The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using ENPP6 antibody at dilution 1/15, on the right is treated with the fusion protein. (Original magnification: x200)

 

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