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Home Antibody All anti-F13A1 antibodies

Anti-F13A1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321062
  • Anti-F13A1 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(2)
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Also for F13A1 (NM_000129)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to C terminal 250 amino acids of human coagulation factor XIII, A1 polypeptide
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.8mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:2000-5000, IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens coagulation factor XIII, A1 polypeptide (F13A1)
Alternative NameF13A
Database LinkNP_000120
Entrez Gene 2162 Human
Entrez Gene 74145 Mouse
Entrez Gene 60327 Rat
FunctionThis gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function; and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits; which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion; the plasma factor XIII dissociates its B subunits and yields the same active enzyme; factor XIIIa; as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules; thus stabilizing the fibrin clot.
Related PathwaySecreted ProteinDruggable Genome Complement and coagulation cascades

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Secreted,Cytoplasm. Positive control: Human esophagus and lung cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using F13A1 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification:x 200)
IHC Image
Predicted cell location: Secreted,Cytoplasm. Positive control: Human esophagus and lung cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human lung cancer tissue using F13A1 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification:x200)

 

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