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Home Antibody All anti-TNFSF10 antibodies

Anti-TNFSF10 Antibody RIK-2

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320501
  • Mouse Anti-Human CD253 (TRAIL) Purified (25 ug)
25ug $120 3-7 Days
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FC(1)
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Also for TNFSF10 (NM_003810)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen
Clone NameRIK-2 Isotype
Species ReactivityHuman Concentration0.5-1mg/ml (lot dependent)
Guaranteed Application *FC Suggested DilutionsFlow, Functional Assay
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified

Reference Data

Target NameHomo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), transcript variant 1
Alternative NameApo-2L; APO2L; CD253; TL2; TRAIL
Database LinkNP_003801
FunctionThe RIK-2 monoclonal antibody reacts with human TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily. TRAIL is not expressed by resting human cells but has been shown to be induced under certain activation conditions. Iin addition it is expressed on several human tumor lines. Interaction of TRAIL with its ligand, Apo-2, induces apoptosis. RIK-2 blocks TRAIL-induced apoptosis.
Related Pathway
Apoptosis
Cytokine-cytokine receptor interaction

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FC Image
Surface staining of human Trail transfected cells with Anti-Human CD253 (TRAIL) PE. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.

 

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