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Anti-TNFSF10 Antibody RIK-2
Also for TNFSF10 (NM_003810)
||0.5-1mg/ml (lot dependent)
||Flow, Functional Assay
|Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Homo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), transcript variant 1|
|Apo-2L; APO2L; CD253; TL2; TRAIL|
|The RIK-2 monoclonal antibody reacts with human TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily. TRAIL is not expressed by resting human cells but has been shown to be induced under certain activation conditions. Iin addition it is expressed on several human tumor lines. Interaction of TRAIL with its ligand, Apo-2, induces apoptosis. RIK-2 blocks TRAIL-induced apoptosis.|
Cytokine-cytokine receptor interaction
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Surface staining of human Trail transfected cells with Anti-Human CD253 (TRAIL) PE. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.