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Home Antibody All anti-TNFRSF10B antibodies

Anti-TNFRSF10B Antibody DJR2-2 (a.k.a. 2-6)

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320491 Mouse Anti-Human CD262 (DR5) Purified (25 ug) 25ug $120 3-7 Days
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Also for TNFRSF10B (NM_003842)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

Immunogen
Clone NameDJR2-2 (a.k.a. 2-6) Isotype
Species ReactivityHuman Concentration0.5-1mg/ml (lot dependent)
Guaranteed Application * Suggested DilutionsFlow, WB
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified

Reference Data

Target Nametumor necrosis factor receptor superfamily member 10b
Alternative NameCD262|DR5|KILLER|KILLER/DR5|TRAIL-R2|TRAILR2|TRICK2|TRICK2A|TRICK2B|TRICKB|ZTNFR9
Database LinkNP_003833
Entrez Gene 8795 Human
FunctionThe DJR2-2 monoclonal antibody reacts with human DR5, also known as TRAIL-R2, Apo2, TRICK2, and KILLER. DR5 binds to TRAIL, activates NF-κB, and induces TRAIL-mediated apoptosis. DR5 is expressed broadly by normal tissues as well as several tumor cells.
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interactionp53 signaling pathwayApoptosisNatural killer cell mediated cytotoxicity

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

 

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