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Home Antibody All anti-CD27 antibodies

Anti-CD27 Antibody LG.7F9

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA320252
  • Hamster Anti-CD27 Purified (100 ug)
100ug $120 3-7 Days
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FC(1)

OriGene Data

Immunogen
Clone NameLG.7F9 Isotype
Species ReactivityHuman, Mouse, Rat Concentration0.5-1mg/ml (lot dependent)
Guaranteed Application *FC Suggested DilutionsFlow, Functional Assay, IP
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified

Reference Data

Target NameHomo sapiens CD27 molecule (CD27)
Alternative NameS152; S152. LPFS2; T14; TNFRSF7; Tp55
Database LinkNP_001233
Entrez Gene 939 Human
Entrez Gene 21940 Mouse
Entrez Gene 500318 Rat
FunctionThe LG.7F9 monoclonal antibody reacts with mouse CD27, a lymphocyte-specific member of the TNFR superfamily. CD27 is expressed by virtually all mature T cells and by a subpopulation of B cells, mainly memory B cells. In mouse, CD27 has been found on nearly all thymocytes excluding a population of CD46-CD8- precursors. CD27 binds to CD70 and, through this interaction, plays an important role in T cell-B cell interaction. It has been reported that triggering CD27 plays an important role in the maturation of CD4+ and CD8+ effector cells. LG.7F9 cross-reacts with human and rat CD27.
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Staining of mouse splenocytes with 0.25 ug Hamster IgG Isotype Control Purified (open histogram) or 0.25 ug Anti-CD27 Purified (filled histogram) followed by Anti-Armenian Hamster IgG FITC . Total viable cells were used for analysis.
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