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Anti-CD27 Antibody LG.7F9
Also for CD27 (NM_001242)
|Human, Mouse, Rat
||0.5-1mg/ml (lot dependent)
||Flow, Functional Assay, IP
|Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Affinity purified (Protein A or G Sepharose)
|Homo sapiens CD27 molecule (CD27)|
|S152; S152. LPFS2; T14; TNFRSF7; Tp55|
|The LG.7F9 monoclonal antibody reacts with mouse CD27, a lymphocyte-specific member of the TNFR superfamily. CD27 is expressed by virtually all mature T cells and by a subpopulation of B cells, mainly memory B cells. In mouse, CD27 has been found on nearly all thymocytes excluding a population of CD46-CD8- precursors. CD27 binds to CD70 and, through this interaction, plays an important role in T cell-B cell interaction. It has been reported that triggering CD27 plays an important role in the maturation of CD4+ and CD8+ effector cells. LG.7F9 cross-reacts with human and rat CD27.|
Cytokine-cytokine receptor interaction
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Staining of mouse splenocytes with 0.25 ug Hamster IgG Isotype Control Purified (open histogram) or 0.25 ug Anti-CD27 Purified (filled histogram) followed by Anti-Armenian Hamster IgG FITC . Total viable cells were used for analysis.