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Home Antibody All anti-LRRTM3 antibodies

Anti-LRRTM3 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320177
  • Rabbit Polyclonal LRRTM3 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403607) , 20ug
100ug $325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for LRRTM3 (NM_178011)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenLRRTM3 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human LRRTM3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.5 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferLRRTM3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification LRRTM3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens leucine rich repeat transmembrane neuronal 3 (LRRTM3)
Alternative NameMGC131810
Database LinkNP_821079
FunctionLRRTM3 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the Abeta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma Abeta42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.
Related Pathway

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WB Image
Western blot analysis of LRRTM3 in mouse brain tissue lysate with LRRTM3 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.
IHC Image
Immunohistochemistry of LRRTM3 in human brain tissue with LRRTM3 antibody at 2.5 ug/mL
IF Image
Immunofluorescence of LRRTM3 in human brain tissue with LRRTM3 antibody at 20 ug/mL.

 

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