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Home Antibody All anti-LRRTM3 antibodies

Anti-LRRTM3 Antibody Polyclonal


Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit Polyclonal LRRTM3 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403607) , 20ug Explanation
100ug $325 3-7 Days
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OriGene Data

ImmunogenLRRTM3 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human LRRTM3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.5 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferLRRTM3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification LRRTM3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens leucine rich repeat transmembrane neuronal 3 (LRRTM3), transcript variant 1
Alternative NameMGC131810
Database LinkNP_821079
Entrez Gene 347731 Human
Entrez Gene 216028 Mouse
Entrez Gene 294380 Rat
FunctionLRRTM3 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the Abeta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma Abeta42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LRRTM3 in mouse brain tissue lysate with LRRTM3 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.
IHC Image
Immunohistochemistry of LRRTM3 in human brain tissue with LRRTM3 antibody at 2.5 ug/mL
IF Image
Immunofluorescence of LRRTM3 in human brain tissue with LRRTM3 antibody at 20 ug/mL.


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